Turkish Archives of Pediatrics

Rare Autoinflammatory Diseases


Division of Rheumatology, Department of Pediatrics, Hacettepe University Faculty of Medicine, Ankara, Turkey

Turk Arch Pediatr 2022; 57: 18-25
DOI: 10.5152/TurkArchPediatr.2022.21303
Read: 363 Downloads: 141 Published: 01 January 2022

Systemic autoinflammatory diseases are disorders caused by dysregulation of the innate immune system leading to systemic inflammation. Since the first gene had been identified causing Familial Mediterranean Fever, the most common hereditary systemic autoinflammatory disease, advances in genomic techniques and awareness of the diseases have led to identifying more genes causing autoinflammatory conditions affecting different parts of the innate immune system. The aim of this review is to provide an update on some recently discovered autoinflammatory conditions and raise awareness for the clinicians. We focused on the actinopathies, interferonopathies, and NF-κB-mediated autoinflammatory diseases. 

Cite this article as: Başaran Ö, Bilginer Y, Özen S. Rare autoinflammatory diseases. Turk Arch Pediatr. 2022;57(1):18-25.

EISSN 2757-6256