Turkish Archives of Pediatrics
Original Article

Birth Weight Reference Percentiles by Gestational Age for Turkish Twin Neonates


Department of Neonatology, Goztepe Training and Research Hospital, SB Istanbul Medeniyet University, Istanbul, Turkey


Department of Preventive Oncology, Institute of Oncology, Hacettepe University, Ankara, Turkey


Department of Pediatrics, American Hospital, Istanbul, Turkey


Department of Pediatrics, Sancaktepe Şehit Prof. Dr. İlhan Varank Education and Research Hospital, University of Health Sciences, Istanbul, Turkey


Neonatal Intensive Care Unit, Zeynep Kamil Maternity and Children Training and Research Hospital, Istanbul, Turkey


Department of Pediatrics, Koç University School of Medicine, Istanbul, Turkey

Turk Arch Pediatr 2021; 56: 316-321
DOI: 10.5152/TurkArchPediatr.2021.20259
Read: 3885 Downloads: 576 Published: 01 July 2021

Aims: In clinical practice, birth weight reference percentiles for singletons are used to evaluate  twin births. The utilization of singleton reference percentiles for twins is not appropriate as they experience different growth trajectories. However, Turkey still lacks such references. Our aim was to create gestational age-specific birth weight references for female and male Turkish twins.

Materials and Methods: This is a hospital-based, multi-centered, retrospective study. In total, 2544 live-born twins between 2010 and 2019 were included in the study. Gestational age, birth weight, mode of delivery, gender, birth order, chorionicity, maternal age, pregnancy resulting from assisted reproduction techniques, APGAR (Appearance, Pulse, Grimace, Activity, and Respiration) score at 5 minutes, admission to the neonatal intensive care unit (NICU), length of stay in NICU, and death during the NICU stay were recorded.

Results: Smoothed reference curves for birth weight by gestational age and separate tables for female and male twin neonates for the 3rd, 10th, 50th, 90th, and 97th percentiles from 26 to 39 weeks of gestational age were constructed. Overall neonatal and infant mortality rates during NICU stay in our twin cohort were 12/1000 and 16/1000, respectively.

Conclusion: Twin-specific birth weight nomograms could be helpful as a reference for clinicians to identify high-risk neonates and fetuses who need specialized care. However, further studies with larger series are urgently needed for validation and use of these nomograms in clinical practice.

Cite this article as: Yalin Imamoglu E, Hayran M, Mahir Kayiran S, et al. Birth weight reference percentiles by gestational age for turkish twin neonates. Turk Arch Pediatr. 2021; 56(4): 316-321.

EISSN 2757-6256